Anti-GPR50 Antibody Picoband®

G protein-coupled receptor 50 is a protein which in humans is encoded by the GPR50 gene. This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women.

Boster Bio Anti-GPR50 Antibody Picoband® catalog # A07827-2. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Protein SOX-15; Protein SOX-12; Protein SOX-20; SOX15; SOX12; SOX20; SOX26; SOX27

GPR50

9248

Q13585

Human, Mouse

No cross-reactivity with other proteins.

E.coli-derived human GPR50 recombinant protein (Position: K214-S471) .

Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.

WB, ELISA

Golgi Proteins, Protein Trafficking, Signal Transduction, Vesicle Transport

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Binds to the 5'-AACAAT-3' sequence.

1. Gubitz, A. K., Reppert, S. M. Assignment of the melatonin-related receptor to human chromosome X (GPR50) and mouse chromosome X (Gpr50) . Genomics 55: 248-251, 1999. 2. Levoye, A., Dam, J., Ayoub, M. A., Guillaume, J.-L., Couturier, C., Delagrange, P., Jockers, R. The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization. EMBO J. 25: 3012-3023, 2006. 3. Reppert, S. M., Weaver, D. R., Ebisawa, T., Mahle, C. D., Kolakowski, L. F., Jr. Cloning of a melatonin-related receptor from human pituitary. FEBS Lett. 386: 219-224, 1996.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A07827-2

49229 MW

67 kDa

SRY-box 15

Nucleus.

Chromaffin granule amine transporter

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.