Anti-GPR75 Antilichaam

Boster Bio Anti-GPR75 Antibody catalog # A13384. Tested in WB, IF, ELISA applications. This antibody reacts with Human, Mouse.

Probable G-protein coupled receptor 75; GPR75

GPR75

O95800

Human, Mouse

The antiserum was produced against synthesized peptide derived from human GPR75. AA range:381-430

Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer. Also expressed by islet cells (at protein level) . .

WB, IF, ELISA

The antibody was affinity-purified from rabbit anti-serum by affinity-chromatography.

1 mg/mL

Liquid

G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A13384

59359 MW

Probable G-protein coupled receptor 75

Cell membrane; Multi-pass membrane protein .

IgG

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.