Anti-HBD Antibody Picoband® 31.0647 Vervoeging

Hemoglobin subunit delta is a protein that in humans is encoded by the HBD gene. The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'.

Hemoglobin subunit delta; Delta-globin; Hemoglobin delta chain; HBD

HBD

3045

P02042

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human HBD recombinant protein (Position: M1-H147) .

Red blood cells.

Flow Cytometry

Biochemicals, Chemical Type, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction

Immunogen affinity purified.

Liquid

Involved in oxygen transport from the lung to the various peripheral tissues.

1. Giardina B, Messana I, Scatena R, Castagnola M (1995) . The multiple functions of hemoglobin.. Crit. Rev. Biochem. Mol. Biol. 30 (3) : 165–96. 2. Higgs DR, Vickers MA, Wilkie AO, Pretorius IM, Jarman AP, Weatherall DJ (May 1989) . A review of the molecular genetics of the human alpha-globin gene cluster. Blood. 73 (5) : 1081–104.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Hemoglobin subunit delta

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.