Anti-hCG receptor/LHCGR Antibody Picoband®

The luteinizing hormone/choriogonadotropin receptor is a member of a subfamily of G protein-coupled receptors (GPCR) characterized by the presence of a large N-terminal extracellular domain containing several leucine-rich repeats (LRR) . This glycoprotein hormone receptor family has been named the LRR-containing GPCR (LGR) family. The LHCGR gene contains 11 exons and spans approximately 80 kb and it is mapped to chromosome 2p21. In the ovary, theca, stromal, late-stage (luteinizing) granulosa, and luteal cells contain LHCGR. In the testes, Leydig cells contain LHCRG.

Boster Bio Anti-hCG receptor/LHCGR Antibody catalog # PA1552. Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Lutropin-choriogonadotropic hormone receptor; LH/CG-R; Luteinizing hormone receptor; LHR; LSH-R; LHCGR; LCGR, LGR2, LHRHR

LHCGR

3973

P22888

Human, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the N-terminus of human hCG receptor, different from the relative rat sequence by two amino acids, mouse sequence by three amino acids.

Gonadal and thyroid cells.

IHC, WB

Endocrine System, G Protein Signaling, More Gpcr, Neuroscience, Neurotransmission, Receptors / Channels, Signal Transduction, Signaling Pathway

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

1. Ascoli, M., Fanelli, F., Segaloff, D. L.The lutropin/choriogonadotropin receptor, a 2002 perspective.Endocr. Rev. 23: 141-174, 2002. 2. Themmen, A. P. N., Huhtaniemi, I. T.Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function.Endocr. Rev. 21: 551-583, 2000.

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=PA1552

78643 MW

78 kDa

No cross reactivity with other proteins.

Lutropin-choriogonadotropic hormone receptor

Cell membrane; Multi-pass membrane protein.

Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.

Lutropin-choriogonadotropic hormone receptor (LH/CG-R)

Rabbit IgG

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.