Anti-HDAC6/Histone Deacetylase 6 Konijn Monoklonale Antilichaam

Boster Bio Anti-HDAC6/Histone Deacetylase 6 Rabbit Monoclonal Antibody catalog # M00595. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

Histone deacetylase 6; HD6;3.5.1.98; HDAC6; KIAA0901; JM21

HDAC6

10013

Q9UBN7

Human

A synthesized peptide derived from human HDAC6

Clone: HEE-8

T-cells and endothelial cells.

WB, IHC, ICC, IF, IP

Acetylation, Chromatin Modifying Enzymes, Epigenetics and Nuclear Signaling, Signaling Pathways, Stem Cells

Affinity-chromatography

0.5mg/ml

Liquid

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity) . Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M00595

131419 MW

160 kDa

Histone deacetylase 6

Nucleus. Cytoplasm. Perikaryon . Cell projection, dendrite . Cell projection, axon . It is mainly cytoplasmic, where it is associated with microtubules.

T-cell surface glycoprotein CD4

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.