Anti-HEMGN-antilichaam (C-term)
Gecertificeerd

Anti-HEMGN-antilichaam (C-term)

Catalog #: A08422-80ul
Maat: 80 µL

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Technische Documentatie

Technische Specificaties

Background

Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB) .

Description

Boster Bio Anti-HEMGN Antibody (C-term) (Catalog # A08422) . Tested in WB application (s) . This antibody reacts with Human.

Synonyms

Hemogen, Erythroid differentiation-associated gene protein, EDAG-1, Hemopoietic gene protein, Negative differentiation regulator protein, HEMGN, EDAG, NDR

Gene Name

HEMGN

UniProt

Q9BXL5

Host

• Rabbit

Reactivity

Human

Immunogen

This HEMGN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 355-389 amino acids from the C-terminal region of human HEMGN.

Clonality

• Polyclonal

Tissue Specificity

Expressed in hematopoietic precursor cells, thyroid and spermatids (at protein level) . Expressed in bone marrow, testis, thymus. Expressed in prostate cancer and ovarian cancer. Also expressed in thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia

Applications

WB

Field of Research

Signal Transduction, Stem Cells

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB) .

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Product MSDS

https://www.bosterbio.com/msds?sku=A08422

Observed Molecular Weight

55341 Da

Applications Notes

WB: 1:2000

Subcellular Location

Nucleus.

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Beschrijving

Boster Bio Anti-HEMGN Antibody (C-term) (Catalog # A08422) . Tested in WB application (s) . This antibody reacts with Human.

Specificaties

ProductnaamAnti-HEMGN-antilichaam (C-term)
Categorie
Beschikbare grootte80 µL
CatalogusnummerA08422-80ul