Anti-hemoglobine/HBA1/HBA2 Antibody Picoband® fluoro647 Vervoeging

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

Hemoglobin subunit alpha; Alpha-globin; Hemoglobin alpha chain; HBA1; HBA2

HBA1/HBA2

3039/3040

P69905

Human, Mouse

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human Hemoglobin/HBA1/HBA2, identical to the related mouse and rat sequences.

Red blood cells.

Flow Cytometry

Adaptive Immunity, Cancer, Cytokines, Immunology, Innate Immunity, Interleukins, Tumor Immunology

Immunogen affinity purified.

Liquid

Involved in oxygen transport from the lung to the various peripheral tissues.

1. Entrez Gene: HBA1 hemoglobin, alpha 1. 2. Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (September 2005) . A human protein-protein interaction network: a resource for annotating the proteome. Cell. 122 (6) : 957–68.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

15258 MW

6

Hemoglobin subunit alpha

Secreted.

Hemoglobin subunit alpha

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.