Anti-HEPACAM familielid 2 HEPACAM2 Antilichaam

HEPACAM2 (Hepatocyte cell adhesion molecule 2), a type I N-linked transmembrane glycoprotein, belongs to the immunoglobulin superfamily. The exact function of HEPACAM2 is currently unknown, but the related protein HEPACAM forms cishomodimers on the cell surface to regulate the cell adhesion and may inhibit cell growth through suppression of cell proliferation. HEPACAM and HEPACAM2 mRNA are differentially regulated in canine tumors, with HEPACAM2 mRNA showing increased levels in adenomas, but decreased levels in metastatic carcinomas compared to normal tissues, while HEPACAM protein levels decreased in adenomas. It is therefore likely that HEPACAM2 plays a different role than HEPACAM in the development and progression to tumors.

Boster Bio Anti-HEPACAM family member 2 HEPACAM2 Antibody (Catalog # A12313) . Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

MIKI, MIKI, UNQ305/PRO346, HEPACAM family member 2, Mitotic kinetics regulator

HEPACAM2

A8MVW5

Human, Mouse, Rat

HEPACAM2 antibody is human, mouse and rat reactive. At least two isoforms of HEPACAM2 are known to exist; this antibody will detect both isoforms. HEPACAM2 antibody is predicted to not cross-react with HEPACAM.

Rabbit polyclonal HEPACAM2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human HEPACAM2. The immunogen is located within amino acids 370 - 420 of HEPACAM2.

Widely expressed.

ELISA, WB

Cancer, Cell Cycle

HEPACAM2 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes: anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation.

HEPACAM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A12313

51407 MW

HEPACAM family member 2

Golgi apparatus membrane

Bovine

HEPACAM family member 2

IgG

HEPACAM2 Antibody is supplied in PBS containing 0.02% sodium azide.