Anti-HIF-1 beta ARNT Konijn Monoklonale Antilichaam

Boster Bio Anti-HIF-1 beta ARNT Rabbit Monoclonal Antibody catalog # M02263. Tested in WB, IHC applications. This antibody reacts with Human.

Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor, nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta; ARNT; BHLHE2

ARNT

405

P27540

Human

A synthesized peptide derived from human HIF-1 beta

Clone: EAD-1

Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable. .

WB, IHC

Cancer, Cancer Metabolism, Epigenetics and Nuclear Signaling, Metabolism, Metabolism Processes, Neural Signal Transduction, Neurology Process, Neuroscience, Pathways and Processes, Pol II Transcription, Polymerase Associated Factors, Response To Hypoxia, Transcription, Transcription Factors

Affinity-chromatography

0.5mg/ml

Liquid

Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M02263

86636 MW

16 kDa

Aryl hydrocarbon receptor nuclear translocator

Nucleus.

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.