Anti-High mobility group proteïne B4 HMGB4 Antibody Picoband®
Gecertificeerd

Anti-High mobility group proteïne B4 HMGB4 Antibody Picoband®

Catalog #: PA1042
Maat: 100 µg/Vial

Kwaliteit

ISO Gecertificeerd

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24-48 uur

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Technische Documentatie

Technische Specificaties

Background

HMGB4 is HMG2 like, isoform 2, high-mobility group box 4. This gene can be found on Chromosome 1. HMGB4 contains two HMG-box regions, which is found in a variety of eukaryotic chromosomal proteins and transcription. HMGB proteins are phosphorylated to various extents reveals that the existence of differentially modified forms increases the number of distinct HMGB protein variants in plant chromatin that may be adapted to certain functions.

Description

Boster Bio Anti-High mobility group protein B4 HMGB4 Antibody catalog # PA1042. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Synonyms

High mobility group protein B4; HMGB4

Gene Name

HMGB4

Gene ID

127540

UniProt

Q8WW32

Host

• Rabbit

Reactivity

Rat, Mouse, Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human HMGB4, different from the related mouse and rat sequences by one amino acid.

Clonality

• Polyclonal

Tissue Specificity

Isoform 3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain. .

Applications

WB

Field of Research

Chromatin Binding Proteins, DNA/RNA Binding, Domain Families, Epigenetics and Nuclear Signaling, Transcription

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. .

References & Citations

1. Phosphorylation of maize and Arabidopsis HMGB proteins by protein kinase CK2alpha.Stemmer C, Leeming DJ, Franssen L, Grimm R, Grasser KD. Institute of Life Sciences, Aalborg University, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Product MSDS

https://www.bosterbio.com/msds?sku=PA1042

Calculated Molecular Weight

22490 MW

Observed Molecular Weight

23 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

High mobility group protein B4

Subcellular Location

Nucleus . Chromosome .

Sequence Similarities

Belongs to the HMGB family.

Protein Name

High mobility group protein B4

Isotype

Rabbit IgG

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Beschrijving

Boster Bio Anti-High mobility group protein B4 HMGB4 Antibody catalog # PA1042. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The bran

Specificaties

ProductnaamAnti-High mobility group proteïne B4 HMGB4 Antibody Picoband®
Categorie
Beschikbare grootte100 µg/Vial
CatalogusnummerPA1042