Anti-Homeobox eiwit Hox-A3 HOXA3 Antibody Picoband® fluoro488 Vervoeging

HOXA3 (HOMEOBOX A3) is a protein that in humans is encoded by the HOXA3 gene, which is also part of the A cluster on chromosome 7. HOXA3 encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Its cytogenetic location is 7q15.2. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA3 protein is able to complement Hoxd3 deficiency when expressed in the context of the Hoxd3 allele.

Homeobox protein Hox-A3; Homeobox protein Hox-1E; HOXA3; HOX1E

HOXA3

3200

O43365

Human, Mouse, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human HOXA3, identical to the related rat and mouse sequences.

Widely expressed.

Flow Cytometry

Developmental Families, Domain Families, Epigenetics and Nuclear Signaling, Transcription

Immunogen affinity purified.

Liquid

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

1. Greer, J. M., Puetz, J., Thomas, K. R., Capecchi, M. R. Maintenance of functional equivalence during paralogous Hox gene evolution. Nature 403: 661-665, 2000. 2. McAlpine PJ, Shows TB (Aug 1990) . Nomenclature for human homeobox genes. 3. Han L, Witmer PD, Casey E, Valle D, Sukumar S (2007) . DNA methylation regulates MicroRNA expression.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

46369 MW

No cross reactivity with other proteins.

6

Homeobox protein Hox-A3

Nucleus.

Belongs to the Antp homeobox family.

Homeobox protein Hox-A3

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.