Anti-Homeobox eiwit Hox-A4 HOXA4 Antibody Picoband® fluoro550 Vervoeging

HOXA4 (HOMEOBOX A4), also known as HOX1D or HOMOLOG OF, is a protein that in humans is encoded by the HOXA4 gene, which is also part of the A cluster on chromosome 7. HOXA4 encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Its cytogenetic location is 7q15.2. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development.

Homeobox protein Hox-A4; Homeobox protein Hox-1.4; Homeobox protein Hox-1D; HOXA4; HOX1D

HOXA4

3201

Q00056

Rat, Mouse, Human

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the N-terminus of human HOXA4, different from the related mouse sequence by two amino acids.

Embryonic nervous system.

Flow Cytometry

Developmental Families, Domain Families, Epigenetics and Nuclear Signaling, Transcription, Transcription Factors

Immunogen affinity purified.

Liquid

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to sites in the 5'-flanking sequence of its coding region with various affinities. The consensus sequences of the high and low affinity binding sites are 5'-TAATGA[CG]-3' and 5'-CTAATTTT- 3'.

1. McAlpine PJ, Shows TB (July 1990) . Nomenclature for human homeobox genes. 2. Scott MP (November 1992) . Vertebrate homeobox gene nomenclature. 3. Entrez Gene: HOXA4 homeobox A4.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

34499 MW

No cross reactivity with other proteins.

6

Homeobox protein Hox-A4

Nucleus.

Belongs to the Antp homeobox family. Deformed subfamily.

Homeobox protein Hox-A4

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.