Anti-Homeobox eiwit Hox-A6 HOXA6 Antibody Picoband® fluoro550 Vervoeging

HOXA6 (HOMEOBOX A6), also known as HOX1B, MOUSE or HOMOLOG OF, is a protein that in humans is encoded by the HOXA6 gene, which is also part of the A cluster on chromosome 7. HOXA6 encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Its cytogenetic location is 7q15.2. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development.

Homeobox protein Hox-A6; Homeobox protein Hox-1B; HOXA6; HOX1B

HOXA6

3203

P31267

Human, Mouse, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence in the middle region of human HOXA6, identical to the related rat and mouse sequences.

Embryonic nervous system.

Flow Cytometry

Transcription, Transcription Factors

Immunogen affinity purified.

Liquid

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

1. Acampora, D., D'Esposito, M., Faiella, A., Pannese, M., Migliaccio, E., Morelli, F., Stornaiuolo, A., Nigro, V., Simeone, A., Boncinelli, E. The human HOX gene family. Nucleic Acids Res. 17: 10385-10402, 1989. 2. Balling, R., Mutter, G., Gruss, P., Kessel, M. Craniofacial abnormalities induced by ectopic expression of the homeobox gene Hox-1.1 in transgenic mice. Cell 58: 337-347, 1989. 3. McAlpine PJ, Shows TB (Aug 1990) . Nomenclature for human homeobox genes.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

26339 MW

No cross reactivity with other proteins.

6

Homeobox protein Hox-A6

Nucleus.

Belongs to the Antp homeobox family.

Homeobox protein Hox-A6

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.