Anti-HP1 alpha CBX5 Konijn Monoklonale Antilichaam

Boster Bio Anti-HP1 alpha CBX5 Rabbit Monoclonal Antibody catalog # M02780. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha; CBX5; HP1A

CBX5

23468

P45973

Human, Mouse, Rat

A synthesized peptide derived from human HP1 alpha

Clone: DHO-3

Widely expressed.

WB, IHC, ICC, IF, IP, Flow Cytometry

2339, Chromatin Binding Proteins, Epigenetics and Nuclear Signaling, Nucleus, Subcellular Markers, Tags & Cell Markers

Affinity-chromatography

0.5mg/ml

Liquid

Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph) . Can interact with lamin-B receptor (LBR) . This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M02780

22225 MW

70 kDa, 90 kDa

Chromobox protein homolog 5

Nucleus . Chromosome . Chromosome, centromere . Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphase.

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.