Anti-HSD17B8 Antilichaam

Boster Bio Anti-HSD17B8 Antibody catalog # A08741. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Estradiol 17-beta-dehydrogenase 8;1.1.1.62

HSD17B8

Q92506

Human, Mouse, Rat

Recombinant fusion protein of human HSD17B8 (NP_055049.1) .

Highly expressed in placenta, liver and pancreas, lower in the skeletal muscle and kidney. Widely expressed.

WB, IHC, ICC, IF

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone (PubMed:17978863) . The heterotetramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis (PubMed:19571038, PubMed:25203508) . Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD (PubMed:25203508) .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A08741

26974 MW

Estradiol 17-beta-dehydrogenase 8

Mitochondrion matrix

Estradiol 17-beta-dehydrogenase 8

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2