Anti-HSP25 Monoklonale Antilichaam (Kloon: IAP-9)

The heat-shock proteins (HSPs) belong to a larger group of polypeptides, the stress proteins, that are induced in various combinations in response to environmental challenges and developmental transitions. Heat-shock 27-kD protein1also knows as HSPB. Synthesis of the small (27-kD) HSP has been shown to be correlated with the acquisition of thermotolerance. HSP27 gene is mapped to 7q11.23. Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin.

Heat shock protein beta-1; HspB1; Heat shock 27 kDa protein; HSP 27; Hspb1; Hsp27

HSPB1

3315

P42930

Human

Partially purified inhibitor of actin polymerization (IAP) protein from turkey gizzard smooth muscle.

Heat shock protein beta-1

IAP-9

ICC, WB

Ascites

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/mL.

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Western blot : 0.5-2μg/ml; Immunohistochemistry (Paraffin-embedded Section) : 1-2μg/ml; Immunohistochemistry (Frozen Section) : 1-2μg/ml; Immunocytochemistry : 1μg/ml

Mouse IgG1