Anti-HSP47 Monoklonale Antilichaam (Kloon: 1C4-1A6)

HSP47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of HSP47 around fibrotic lesions. The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since HSP47 binds a single substrate. Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils.

SERPINH1||CBP1||CBP2||HSP47||SERPINH2||PIG14

SERPINH1

871

P50454

Human

Human HSP47, full length

1C4-1A6

WB, ICC/IF

Protein G Purified

PBS pH7.4, 50% glycerol, 0.09% sodium azide

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

WB (1:1000), ICC/IF (1:100) ; optimal dilutions for assays should be determined by the user.

Mouse IgG1 Kappa

Unconjugated