Anti-HSP70 Monoklonale Antilichaam (Kloon: BRM-22)

Heat-shock proteins, or stress proteins, are expressed in response to heat shock and a variety of other stress stimuli including oxidative free radicals and toxic metal ions. Sargent et al. identified a duplicated HSP70 locus in the class III region of the major histocompatibility complex on 6p21.3. A duplicated locus encoding the major heat shock-induced protein HSP70 is located in the major histocompatibility complex (MHC) class III region 92 kilobases (kb) telomeric to the C2 gene. The 70-kd mammalian heat shock proteins are structurally and functionally related to the uncoating protein that releases clathrin triskelia from coated vesicles.

Heat shock 70 kDa protein 1B; Heat shock 70 kDa protein 1; HSP70.1; Hspa1b; Hcp70.1, Hsp70-1, Hsp70a1, Hspa1

Hspa1b

15511

P17879

Human

HSP70 isolated from bovine brain.

Heat shock 70 kDa protein 1A/1B

BRM-22

WB, IHC-P, IHC-F

Ascites

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/mL.

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Western blot : 0.5μg/ml; Immunohistochemistry (Paraffin-embedded Section) : 0.5-1μg/ml; Immunohistochemistry (Frozen Section) : 0.5-1μg/ml

Mouse IgG1