Anti-Hsp75 TRAP1 Konijn Monoklonale Antilichaam

Boster Bio Anti-Hsp75 TRAP1 Rabbit Monoclonal Antibody catalog # M02426-1. Tested in WB, IP applications. This antibody reacts with Human.

Heat shock protein 75 kDa, mitochondrial; HSP 75; TNFR-associated protein 1; Tumor necrosis factor type 1 receptor-associated protein; TRAP-1; TRAP1; HSP75

TRAP1

10131

Q12931

Human

A synthesized peptide derived from human Hsp75

Clone: IBD-20

Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung, placenta and bladder. Expression is higly reduced in bladder cancer and renal cell carcinoma specimens compared to healthy tissues, but it is increased in other type of tumors. .

WB, IP

Apoptosis, Cancer, Cell Biology, Cell Death, Chaperones, Heat Shock Proteins, Metabolism, Metabolism Processes, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Pathways and Processes, Protein Trafficking, Signal Transduction

Affinity-chromatography

0.5mg/ml

Liquid

Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M02426-1

80110 MW

35 kDa, 39 kDa

Heat shock protein 75 kDa, mitochondrial

Mitochondrion . Mitochondrion inner membrane . Mitochondrion matrix .

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.