Anti-HTRA4 Antibody Picoband® 31.0550 Vervoeging

This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.

HTRA4

203100

P83105

Human

E.coli-derived human HTRA4 recombinant protein (Position: A31-D464) . Human HTRA4 shares 68.7% and 68.9% amino acid (aa) sequence identity with mouse and rat HTRA4, respectively.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Clausen, T., Southan, C., Ehrmann, M. The HtrA family of proteases: implications for protein composition and cell fate. Molec. Cell 10: 443-455, 2002. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 1/12/2007.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.