Anti-ICAM1 Antibody Picoband® (monoklonale, 6F2C3) fluoro550 Vervoeging
Gecertificeerd

Anti-ICAM1 Antibody Picoband® (monoklonale, 6F2C3) fluoro550 Vervoeging

Catalog #: M00171-3-Fluoro550
Maat: 100 µg/Vial

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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BTW niet inbegrepen
Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Background

CD54, also known as ICAM-1. Intercellular adhesion molecule-1 (ICAM1) is a ligand for lymphocyte function-associated (LFA) antigens. ICAM-1 is an integral membrane protein, a member of the immunoglobulin superfamily, and a ligand for LFA-1, a beta 2 leukocyte integrin. This protein is the major human rhinovirus receptor. The ICAM1 gene is mapped to human chromosome 19. In humans, lymphocyte adhesion to cells is mediated by the protein heterodimer CD11a/CD18 (Leu-CAMa, LFA-1) and its ligand CD54 (ICAM-1) .

Synonyms

Solute carrier family 2, facilitated glucose transporter member 1; Glucose transporter type 1, erythrocyte/brain; GLUT-1; HepG2 glucose transporter; SLC2A1; GLUT1

Gene Name

ICAM1

Gene ID

3383

UniProt

P05362

Host

• Mouse

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E. coli-derived human ICAM1 recombinant protein (Position: Q28-R268) .

Clonality

• Monoclonal

Clone

Clone: 6F2C3

Tissue Specificity

Detected in erythrocytes (at protein level) . Expressed at variable levels in many human tissues.

Applications

Flow Cytometry

Field of Research

Channels, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Plasma Membrane, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.

References & Citations

1. Ballantyne, C. M.; Kozak, C. A.; O'Brien, W. E.; Beaudet, A. L. : Assignment of the gene for intercellular adhesion molecule-1 (Icam-1) to proximal mouse chromosome 9. Genomics 9: 547-550, 1991. 2. Greve, J. M.; Davis, G.; Meyer, A. M.; Forte, C. P.; Yost, S. C.; Marlor, C. W.; Kamarck, M. E.; McClelland, A. : The major human rhinovirus receptor is ICAM-1. Cell 56: 839-847, 1989. 3. Prieto, J.; Takei, F.; Gendelman, R.; Christenson, B.; Biberfeld, P.; Patarroyo, M. : MALA-2, mouse homologue of human adhesion molecule ICAM-1 (CD54) . Europ. J. Immun. 19: 1551-1557, 1989.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

46659 MW

Applications Notes

6

Gene Name Synonym

Solute carrier family 2 (facilitated glucose transporter), member 1

Subcellular Location

Cell membrane. Multi-pass membrane protein. Melanosome.

Protein Name

Isocitrate dehydrogenase [NADP] cytoplasmic

Isotype

Mouse IgG1

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Beschrijving

Anti-ICAM1 Antibody Picoband® (monoklonale, 6F2C3) fluoro550 Vervoeging Beschikbaar in 100 µg/Vial. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamAnti-ICAM1 Antibody Picoband® (monoklonale, 6F2C3) fluoro550 Vervoeging
Categorie
Beschikbare grootte100 µg/Vial
CatalogusnummerM00171-3-Fluoro550