Anti-IDH2 Monoklonale antilichamen
Gecertificeerd

Anti-IDH2 Monoklonale antilichamen

Catalog #: M00510
Maat: 100 µL/Vial

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Description

Boster Bio Anti-IDH2 Monoclonal Antibody catalog # M00510. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Synonyms

Glucocorticoid receptor; GR; Nuclear receptor subfamily 3 group C member 1; NR3C1; GRL

Gene Name

IDH2

Gene ID

3418

UniProt

P48735

Host

• Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human IDH2 Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex.

Clonality

• Monoclonal

Clone

Clone: ACFO-9

Tissue Specificity

Widely expressed. In the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart. .

Applications

WB, IHC, Flow Cytometry

Field of Research

Cancer, Cancer Metabolism, Energy Metabolism, Energy Transfer Pathways, Integration Of Energy, Integration Of Energy Metabolism, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Pathways and Processes, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Receptor for glucocorticoids (GC) . Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product MSDS

https://www.bosterbio.com/msds?sku=M00510

Calculated Molecular Weight

85659 MW

Observed Molecular Weight

30 kDa

Gene Name Synonym

Glucocorticoid receptor

Subcellular Location

Cytoplasm . Mitochondrion. Nucleus . Cytoplasmic in the absence of ligand, nuclear after ligand- binding.

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Beschrijving

Boster Bio Anti-IDH2 Monoclonal Antibody catalog # M00510. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Specificaties

ProductnaamAnti-IDH2 Monoklonale antilichamen
Categorie
Beschikbare grootte100 µL/Vial
CatalogusnummerM00510