Anti-IGBP1 Antibody Picoband® 31.0550 Vervoeging

Immunoglobulin-binding protein 1 is a protein that in humans is encoded by the IGBP1 gene. The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways.

B-cell CLL/lymphoma 9-like protein; B-cell lymphoma 9-like protein; BCL9-like protein; Protein BCL9-2; BCL9L; DLNB11

IGBP1

3476

P78318

Human

No cross-reactivity with other proteins.

E.coli-derived human IGBP1 recombinant protein (Position: D47-I208) .

Expressed in breast, ductal and invasive ductal carcinomas of the breast, sporadic colorectal adenomas and carcinomas (at protein level) . Expressed in fetal brain. Expressed in lung, amygdala, eye, prostate, pancreatic and prostate cancers, head and neck tumors and embryonal tumor.

Flow Cytometry

Cell Biology, Cell Cycle, Cell Differentiation, G Protein Signaling, Regulators, Signal Transduction, Signaling Pathway, Small G Proteins

Immunogen affinity purified.

Liquid

Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1.

1. Di Como, C. J., Arndt, K. T. Nutrients, via the Tor proteins, stimulate the association of Tap42 with type 2A phosphatases. Genes Dev. 10: 1904-1916, 1996. 2. Graham, J. M., Jr., Wheeler, P., Tackels-Horne, D., Lin, A. E., Hall, B. D., May, M., Short, K. M., Schwartz, C. E., Cox, T. C. A new X-linked syndrome with agenesis of the corpus callosum, mental retardation, coloboma, micrognathia, and a mutation in the alpha 4 gene at Xq13. Am. J. Med. Genet. 123A: 37-44, 2003. 3. Inui, S., Kuwahara, K., Mizutani, J., Maeda, K., Kawai, T., Nakayasu, H., Sakaguchi, N. Molecular cloning of a cDNA clone encoding a phosphoprotein component related to the Ig receptor-mediated signal transduction. J. Immun. 154: 2714-2723, 1995.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

BCL9 like

Nucleus.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.