Anti-Ikaros Monoklonale Antilichaam

Boster Bio Anti-Ikaros Monoclonal Antibody catalog # M00531-1. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Zinc finger protein GLI1; Glioma-associated oncogene; Oncogene GLI; GLI1; GLI

IKZF1

10320

Q13422

Human, Mouse, Rat

A synthesized peptide derived from human Ikaros Transcription regulator of hematopoietic cell differentiation (PubMed:17934067) . Binds gamma-satellite DNA (PubMed:17135265, PubMed:19141594) . Plays a role in the development of lymphocytes, B- and T-cells.

Clone: AEFA-9

Testis, myometrium and fallopian tube. Also expressed in the brain with highest expression in the cerebellum, optic nerve and olfactory tract. .

WB, IHC, Flow Cytometry

Apoptosis, Cancer, Cell Death, Domain Families, Epigenetics and Nuclear Signaling, Invasion/Microenvironment, Transcription, Zinc Finger

Affinity-chromatography

0.5mg/ml

Liquid

Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M00531-1

117904 MW

40 kDa

Zinc finger protein GLI1

Cytoplasm. Nucleus. Tethered in the cytoplasm by binding to SUFU. Activation and translocation to the nucleus is promoted by interaction with STK36. Phosphorylation by ULK3 may promote nuclear localization. Translocation to the nucleus is promoted by interaction with ZIC1.

T-cell surface glycoprotein CD4

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.