Anti-IKB-epsilon NFKBIE Monoklonale antilichamen

Boster Bio Anti-IKB epsilon NFKBIE Monoclonal Antibody catalog # M07073. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

MAD2L1-binding protein; Caught by MAD2 protein; MAD2L1BP; CMT2, KIAA0110

NFKBIE

4794

O00221

Human

A synthesized peptide derived from human IKB epsilon Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.

Clone: ADCF-14

Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level) . Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate. .

WB, IHC, ICC, IF, IP

Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, NFKB Pathway, Nuclear Signaling, Signal Transduction, Signaling Pathway, TLR Signaling, Transcription, Transcription Factors

Affinity-chromatography

0.5mg/ml

Liquid

May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M07073

31052 MW

116 kDa

MAD2L1-binding protein

Nucleus. Cytoplasm, cytoskeleton, spindle. During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.