Anti-IL-28 IFNL2 Antilichaam

Boster Bio Anti-IL-28 IFNL2 Antibody catalog # A09233. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.

Interferon lambda-2; IFN-lambda-2; Cytokine Zcyto20; Interleukin-28A; IL-28A; IFNL2; IL28A, ZCYTO20

IFNL2

Q8IZJ0

Human, Mouse

The antiserum was produced against synthesized peptide derived from the C-terminal region of human IL28A. AA range:131-180

WB, IHC, IF, ELISA

Immunogen affinity purified

1 mg/mL

Liquid

Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN- stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type- selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR) -induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A09233

22288 MW

Interferon lambda-2

Secreted .

IgG

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.