Anti-ILK/Integrin Linked Ilk Rabbit Monoclonal Antibody

Boster Bio Anti-ILK/Integrin Linked Ilk Rabbit Monoclonal Antibody catalog # M02932. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Integrin-linked protein kinase;2.7.11.1;59 kDa serine/threonine-protein kinase; ILK-1; ILK-2; p59ILK; ILK; ILK1, ILK2

ILK

3611

Q13418

Human, Mouse, Rat

A synthesized peptide derived from human ILK

Clone: FHE-9

Highly expressed in heart followed by skeletal muscle, pancreas and kidney. Weakly expressed in placenta, lung and liver.

WB, IHC, ICC, IF, IP, Flow Cytometry

Protein Phosphorylation, Signal Transduction, Tyrosine Kinases

Affinity-chromatography

0.5mg/ml

Liquid

Receptor-proximal protein kinase regulating integrin- mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M02932

51419 MW

54 kDa

Integrin-linked protein kinase

Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium . Cytoplasm, myofibril, sarcomere.

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.