Anti-inflammatoire middelen 8
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Anti-inflammatory agent 8 (compound 13) is a tilomisole-based benzimidazothiazole derivative. Anti-inflammatory agent 8 expresses activity on COX-2 enzyme more than COX-1 with an IC50 of 0.09 nM. Anti-inflammatory agent 8 is orally active[1].
1103920-19-9
12352005
COX
Reference compound
Immunology/Inflammation
COVID-19-immunoregulation
Inflammation/Immunology
https://www.medchemexpress.com/anti-inflammatory-agent-8.html
10 mM in DMSO
O=C(C1=C(C)N2C3=CC=CC=C3N=C2S1)NNC(NC4=CC=CC=C4)=S
C18H15N5OS2
381.47
[1] Darwish SA, et al. New tilomisole-based benzimidazothiazole derivatives as anti-inflammatory agents: Synthesis, in vivo, in vitro evaluation, and in silico studies [published online ahead of print, 2022 Jan 29]. Bioorg Chem. 2022;120:105644.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-115920/
Reference compound1
No Development Reported
Beschrijving
Anti-inflammatory agent 8 (compound 13) is a tilomisole-based benzimidazothiazole derivative. Anti-inflammatory agent 8 expresses activity on COX-2 enzyme more
Specificaties
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