Anti-INPP4A Antibody Picoband® fluoro550 Vervoeging

Type I inositol-3,4-bisphosphate 4-phosphatase is an enzyme that in humans is encoded by the INPP4A gene. This gene encodes an Mg++ independent enzyme that hydrolyzes the 4-position phosphate from the inositol ring of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate. Multiple transcript variants encoding distinct isoforms have been described.

Ribosome-binding protein 1; 180 kDa ribosome receptor homolog; RRp; ES/130-related protein; Ribosome receptor protein; RRBP1; KIAA1398

INPP4A

3631

Q96PE3

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human INPP4A recombinant protein (Position: Q39-E935) .

Expressed in kidney.

Flow Cytometry

Cancer, DNA/RNA, Epigenetics and Nuclear Signaling, Ribosome, Translation, Tumor Biomarkers

Immunogen affinity purified.

Liquid

Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane.

1. Joseph, R. E., Walker, J., Norris, F. A. Assignment of the inositol polyphosphate 4-phosphatase type I gene (INPP4A) to human chromosome band 2q11.2 by in situ hybridization. Cytogenet. Cell Genet. 87: 276-277, 1999. 2. Norris, F. A., Auethavekiat, V., Majerus, P. W. The isolation and characterization of cDNA encoding human and rat brain inositol polyphosphate 4-phosphatase. J. Biol. Chem. 270: 16128-16133, 1995. 3. Nystuen, A., Legare, M. E., Shultz, L. D., Frankel, W. N. A null mutation in inositol polyphosphate 4-phosphatase type I causes selective neuronal loss in weeble mutant mice. Neuron 32: 203-212, 2001.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Ribosome binding protein 1

Endoplasmic reticulum membrane, Single-pass type III membrane protein.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.