Anti-Interleukine-7 IL7 Antibody Picoband® fluoroc647 Vervoeging

IL-7, Interleukin 7, is a protein that in humans is encoded by the IL-7 gene. IL-7 a hematopoietic growth factor secreted by stromal cells in the red marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells but is not produced by lymphocytes. By the combination of approaches, IL-7 is located on 8q12-q13. IL-7 is critical for early T-cell development and homeostasis of naive and memory CD8-positive T cells. It signals through the IL-7 receptor complex, which consists of the IL7R-alpha chain and the common IL2R-gamma chain is critical for early T-cell development and homeostasis of naive and memory CD8 -positive T cells. It signals through the IL-7 receptor complex, which consists of the IL7R-alpha chain and the common IL2R-gamma chain.

Interleukin-7; IL-7; IL7

IL7

3574

P13232

Human

No cross-reactivity with other proteins

E. coli-derived human IL-7 recombinant protein (Position: D26-H177) .

Flow Cytometry

Cytokines, Immunology, Innate Immunity, Interleukins

Immunogen affinity purified.

Liquid

Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation.

1. Goodwin RG, Lupton S, Schmierer A, Hjerrild KJ, Jerzy R, Clevenger W, Gillis S, Cosman D, Namen AE (January 1989) . Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells. Proc. Natl. Acad. Sci. U.S.A. 86 (1) : 302–6. 2. Lupton SD, Gimpel S, Jerzy R, et al. (1990) . Characterization of the human and murine IL-7 genes. J. Immunol. 144 (9) : 3592–601. 3. Sutherland GR, Baker E, Fernandez KE, Callen DF, Goodwin RG, Lupton S, Namen AE, Shannon MF, Vadas MA (July 1989) . The gene for human interleukin 7 (IL7) is at 8q12-13. Hum. Genet. 82 (4) : 371–2.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

20187 MW

No cross reactivity with other proteins.

6

Interleukin-7

Secreted.

Belongs to the IL-7/IL-9 family.

Interleukin-7 (IL-7)

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.