Anti-IQGAP1 Monoklonale antilichamen

Boster Bio Anti-IQGAP1 Monoclonal Antibody catalog # M01603. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Cyclic AMP-dependent transcription factor ATF-1; cAMP-dependent transcription factor ATF-1; Activating transcription factor 1; Protein TREB36; ATF1

IQGAP1

8826

P46940

Human, Mouse

A synthesized peptide derived from human IQGAP1 Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane.

Clone: ADGG-9

Ubiquitously expressed, with highest levels in prostate, pancreas and kidney (PubMed:14615060, PubMed:15496141, PubMed:19664597) . Expressed in melanocytes (PubMed:23999003) . .

WB, IHC, ICC, IF, Flow Cytometry

Adapters, Cancer, Cytoplasmic, G Protein Signaling, Regulators, Signal Transduction, Signaling Pathway, Small G Proteins

Affinity-chromatography

0.5mg/ml

Liquid

This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M01603

29233 MW

92 kDa

Cyclic AMP-dependent transcription factor ATF-1

Nucleus.

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.