Anti-IRF2 Konijn Monoklonale Antilichaam

Boster Bio Anti-IRF2 Rabbit Monoclonal Antibody catalog # M02935. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse.

Interferon regulatory factor 2; IRF-2; IRF2

IRF2

3660

P14316

Human, Mouse

A synthesized peptide derived from human IRF2

Clone: HAC-9

Expressed throughout the epithelium of the colon. Also expressed in lamina propria. .

WB, IHC, ICC, IF

Cytokines, Domain Families, Epigenetics and Nuclear Signaling, Hlh/Leucine Zipper, Immunology, Innate Immunity, Interferons, Pol II Transcription, Polymerase Associated Factors, Transcription, Transcription Factors

Affinity-chromatography

0.5mg/ml

Liquid

Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS) ) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M02935

39354 MW

54 kDa

Interferon regulatory factor 2

Nucleus.

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.