Anti-Islet1 Monoklonaal antilichaam

Boster Bio Anti-Islet1 Monoclonal Antibody catalog # M02969-1. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.

Insulin gene enhancer protein ISL-1; Islet-1; ISL1

ISL1

3670

P61371

Human

A synthesized peptide derived from human Islet1 ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry.

Clone: AFIA-9

Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.

WB, IHC, ICC, IF, IP, Flow Cytometry

Neurogenesis, Neurology Process, Neuron Marker, Neuroscience, Organogenesis, Stem Cells, Transcription Factors/Regulators

Affinity-chromatography

0.5mg/ml

Liquid

Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M02969-1

39036 MW

28 kDa

Insulin gene enhancer protein ISL-1

Nucleus.

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.