Anti-ITPKC Antibody Picoband® fluoro488 Vervoeging

This gene encodes a member of the inositol 1,4,5-trisphosphate [Ins (1,4,5) P (3) ] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.

ITPKC

80271

Q96DU7

Human

E.coli-derived human ITPKC recombinant protein (Position: D292-E607) . Human ITPKC shares 88.1% and 88% amino acid (aa) sequence identity with mouse and rat ITPKC, respectively.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Chi, H., Huang, F.-Y., Chen, M.-R., Chiu, N.-C., Lee, H.-C., Lin, S.-P., Chen, W.-F., Lin, C.-L., Chan, H.-W., Liu, H.-F., Huang, L.-M., Lee, Y.-J. ITPKC gene SNP rs28493229 and Kawasaki disease in Taiwanese children. Hum. Molec. Genet. 19: 1147-1151, 2010. 2. Dewaste, V., Pouillon, V., Moreau, C., Shears, S., Takazawa, K., Erneux, C. Cloning and expression of a cDNA encoding human inositol 1,4,5-trisphosphate 3-kinase C. Biochem. J. 352: 343-351, 2000. 3. Hamosh, A. Personal Communication. Baltimore, Md. 5/6/2020.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

75 kDa

6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.