Anti-JAB1 Monoklonaal antilichaam

Boster Bio Anti-JAB1 Monoclonal Antibody catalog # M01849. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Peroxiredoxin-6;1.11.1.15;1-Cys peroxiredoxin;1-Cys PRX;24 kDa protein; Acidic calcium-independent phospholipase A2; aiPLA2;3.1.1.-; Antioxidant protein 2; Liver 2D page spot 40; Non-selenium glutathione peroxidase; NSGPx;1.11.1.9; Red blood cells page spot 12; PRDX6; AOP2, KIAA0106

COPS5

10987

Q92905

Human, Mouse, Rat

A synthesized peptide derived from human JAB1 Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.

Clone: AEEG-3

Weakly expressed in most tissues. Expressed at higher level in heart, brain, kidney and pancreas and also in liver, lung, placenta, prostate and kidney. .

WB, IHC, ICC, IF, IP

Cancer, Cancer Susceptibility, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Deubiquitination, Epigenetics and Nuclear Signaling, Intracellular Signaling, Kinases, Neuroscience, Neurotransmission, p53 Pathway, Proteasome, Proteasome / Ubiquitin, Protein Phosphorylation, Proteolysis/Ubiquitin, Proto-Oncogenes, SCF Complex E3 Ligase, Ser/Thr Kinases, Signal Transduction, Transcription, Ubiquitin & Ubiquitin Like Modifiers, Ubiquitin E3 Enzymes

Affinity-chromatography

0.5mg/ml

Liquid

Involved in redox regulation of the cell. Can reduce H (2) O (2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M01849

21 kDa

Peroxiredoxin-6

Cytoplasm . Lysosome . Cytoplasmic vesicle . Also found in lung secretory organelles. .

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.