Anti-Kappa Lichte Ketting (B-Cell Marker) Monoklonale Antilichaam (Kloon: KLC264) -CF488

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

HCAK1; Ig Kappa Chain C Region; IGKC; Immunoglobulin KM

IGKC

3514

P01601; P01834

Human

Recombinant human Ig kappa chain

KLC264

FACS, IF

Antibody Purified from Bioreactor Concentrate by Protein A/G and conjμgated to various reporter molecules. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide. Contact us if you require this Ab in a different format.

Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous.

Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood) ; Immunofluorescence (1:50-1:100)

Mouse IgG1, kappa

CF488