Anti-KHSRP Antibody Picoband® (monoklonale, 4F10D2)

Far upstream element-binding protein 2 is a protein that in humans is encoded by the KHSRP gene. The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization.

Boster Bio Anti-KHSRP Antibody Picoband® (monoclonal, 4F10D2) catalog # M02770-3. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

N-myc-interactor; Nmi; N-myc and STAT interactor; NMI

KHSRP

8570

Q92945

Human

No cross-reactivity with other proteins.

E.coli-derived human KHSRP recombinant protein (Position: D116-R478) .

Clone: 4F10D2

Expressed in all adult and fetal tissues except brain and skin. More abundant in fetal tissues especially liver.

WB, ICC, IF, Flow Cytometry

Cytoskeleton, Cytoskeleton/ECM, Motor Proteins, Myosin, Signal Transduction

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5.

1. Briata, P., Forcales, S. V., Ponassi, M., Corte, G., Chen, C.-Y., Karin, M., Puri, P. L., Gherzi, R. p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts. Molec. Cell 20: 891-903, 2005. 2. Davis-Smyth, T., Duncan, R. C., Zheng, T., Michelotti, G., Levens, D. The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators. J. Biol. Chem. 271: 31679-31687, 1996. 3. Gherzi, R., Lee, K.-Y., Briata, P., Wegmuller, D., Moroni, C., Karin, M., Chen, C.-Y. A KH domain RNA binding protein, KSRP, promotes ARE-ed mRNA turnover by recruiting the degradation machinery. Molec. Cell 14: 571-583, 2004.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=M02770-3

82 kDa

6

N-myc (and STAT) interactor

Cytoplasm.

Mouse IgG2b

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.