Anti-KLRA1 KLRA1P Antilichaam

KLRA1 (also known and Ly49L) is a member of the LY49 family of receptors Natural killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA1 is thought to be an activating receptor, inducing DAP12 phosphorylation in response to antibody-mediated cross-linking of KLRA1 on NK cells. At least three isoforms of KLRA1 are known to exist.

Boster Bio Anti-KLRA1 KLRA1P Antibody (Catalog # A33934) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Ly49, KLRA#, KLRA1, LY49L, Ly-49L

KLRA1P

EAW96194

Human, Mouse, Rat

KLRA1 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of human KLRA1. The immunogen is located within amino acids 190 - 240 of KLRA1.

High expression in placenta, skeletal muscle, kidney and pancreas tissues. Absent or very faint expression in heart, brain, lung and liver. Expressed during adipogenic differentiation of mesenchymal stem cells (at protein level) .

ELISA, WB, IHC-P, IF

Immunology

KLRA1 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.

KLRA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A33934

6407 MW

Killer cell lectin like receptor A1, pseudogene

Interleukin-16: Secreted.

Killer cell lectin like receptor A1, pseudogene

IgG

KLRA1 Antibody is supplied in PBS containing 0.02% sodium azide.