Anti-KMT5A / SETD8 / Pr-SET7 Monoklonale antilichamen

Boster Bio Anti-KMT5A / SETD8 / Pr-SET7 Monoclonal Antibody catalog # M05349. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Kinesin-like protein KIFC1; Kinesin-like protein 2; Kinesin-related protein HSET; KIFC1; HSET, KNSL2

KMT5A

387893

Q9NQR1

Human, Mouse, Rat

A synthesized peptide derived from human KMT5A / SETD8 / Pr-SET7 Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1) . H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes.

Clone: ADHO-11

Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung.

WB, Flow Cytometry

Chromatin Modifying Enzymes, DNA/Nucleotides, DNA/RNA, Epigenetics and Nuclear Signaling, Methylation

Affinity-chromatography

0.5mg/ml

Liquid

Minus end-ed microtubule-dependent motor required for bipolar spindle formation (PubMed:15843429) . May contribute to movement of early endocytic vesicles (By similarity) . Regulates cilium formation and structure (By similarity) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M05349

73748 MW

72 kDa

Kinesin-like protein KIFC1

Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Early endosome . Associated with nucleus during interphase, centrosomes in early and spindle in later mitosis. .

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.