Anti-Krueppel-achtige factor 5 KLF5 Antibody Picoband® 0,00647 Vervoeging
Gecertificeerd

Anti-Krueppel-achtige factor 5 KLF5 Antibody Picoband® 0,00647 Vervoeging

Catalog #: PA1889-Fluoro647
Maat: 100 µg/Vial

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Background

Reporter gene

Synonyms

Krueppel-like factor 5; Basic transcription element-binding protein 2; BTE-binding protein 2; Colon krueppel-like factor; GC-box-binding protein 2; Intestinal-enriched krueppel-like factor; Transcription factor BTEB2; KLF5; BTEB2, CKLF, IKLF

Gene Name

KLF5

Gene ID

688

UniProt

Q13887

Host

• Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human KLF5, identical to the related rat and mouse sequences.

Clonality

• Polyclonal

Tissue Specificity

Expressed only in testis and placenta.

Applications

Flow Cytometry

Field of Research

Apoptosis, Cancer, Cancer Susceptibility, Cardiovascular, Cell Biology, Domain Families, Epigenetics and Nuclear Signaling, Hypertrophy, Intracellular, Krueppel Like Factor, Mesenchymal Stem Cells, Oncoproteins, Oncoproteins/Suppressors, p53 Pathway, Proto-Oncogenes, Stem Cells, Transcription, Transcription Factors

Purification

Immunogen affinity purified.

Form

Liquid

Function

Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes.

References & Citations

1. Oishi, Y., Manabe, I., Tobe, K., Tsushima, K., Shindo, T., Fujiu, K., Nishimura, G., Maemura, K., Yamauchi, T., Kubota, N., Suzuki, R., Kitamura, T., Akira, S., Kadowaki, T., Nagai, R.Kruppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation.Cell Metab. 1: 27-39, 2005. 2. Shindo, T., Manabe, I., Fukushima, Y., Tobe, K., Aizawa, K., Miyamoto, S., Kawai-Kowase, K., Moriyama, N., Imai, Y., Kawakami, H., Nishimatsu, H., Ishikawa, T., and 10 others.Kruppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.Nature Med. 8: 856-863, 2002. 3. Sogawa, K., Imataka, H., Yamasaki, Y., Kusume, H., Abe, H., Fujii-Kuriyama, Y.cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2.Nucleic Acids Res. 21: 1527-1532, 1993.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

50792 MW

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

Krueppel-like factor 5

Subcellular Location

Nucleus .

Sequence Similarities

Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein Name

Krueppel-like factor 5

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Beschrijving

Anti-Krueppel-achtige factor 5 KLF5 Antibody Picoband® 0,00647 Vervoeging Beschikbaar in 100 µg/Vial. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamAnti-Krueppel-achtige factor 5 KLF5 Antibody Picoband® 0,00647 Vervoeging
Categorie
Beschikbare grootte100 µg/Vial
CatalogusnummerPA1889-Fluoro647