Anti-L1RE1 Antibody Picoband® 31.0647 Vervoeging

Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. May function as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded.

Follicular dendritic cell secreted peptide; FDC secreted protein; FDC-SP; FDCSP; C4orf7; UNQ733/PRO1419

L1RE1

4029

Q9UN81

Human

No cross-reactivity with other proteins

E.coli-derived human L1RE1 recombinant protein (Position: Q147-E324) .

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Flow Cytometry

Immunology, Secreted Molecules

Immunogen affinity purified.

Liquid

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

1. Baillie, J. K., Barnett, M. W., Upton, K. R., Gerhardt, D. J., Richmond, T. A., De Sapio, F., Brennan, P., Rizzu, P., Smith, S., Fell, M., Talbot, R. T., Gustincich, S., Freeman, T. C., Mattick, J. S., Hume, D. A., Heutink, P., Carninci, P., Jeddeloh, J. A., Faulkner, G. J. Somatic retrotransposition alters the genetic landscape of the human brain. Nature 479: 534-537, 2011. 2. Boeke, J. D. LINEs and Alus--the polyA connection. Nature Genet. 16: 6-7, 1997. 3. Brosius, J., Gould, S. J. On 'genomenclature': a comprehensive (and respectful) taxonomy for pseudogenes and other 'junk DNA.' Proc. Nat. Acad. Sci. 89: 10706-10710, 1992.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

9700 MW

6

Follicular dendritic cell secreted peptide

Secreted.

Follicular dendritic cell secreted peptide

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.