Anti-LARP/SEPTIN1 Antibody Picoband® fluoro550 Vervoeging

Septin-1 is a protein that in humans is encoded by the SEPTIN1 gene. This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined.

Lymphocyte antigen 6A-2/6E-1; Ly-6A.2/Ly-6E.1; Stem cell antigen 1; SCA-1; T-cell-activating protein; TAP; Ly6a; Ly6

SEPTIN1

1731

Q8WYJ6

Human, Mouse, Rat

No cross-reactivity with other proteins.

A synthetic peptide corresponding to a sequence at the C-terminus of human LARP/SEPTIN1, identical to the related mouse and rat sequences.

Widely expressed. .

Flow Cytometry

Chemokines, Immunology, Innate Immunity

Immunogen affinity purified.

Liquid

T-cell activation.

1. Hartz, P. A. Personal Communication. Baltimore, Md. 7/1/2009. 2. Nottenburg, G., Gallatin, W. M., St. John, T. Lymphocyte HEV adhesion variants differ in the expression of multiple gene sequences. Gene 95: 279-284, 1990. 3. Qi, M., Yu, W., Liu, S., Jia, H., Tang, L., Shen, M., Yan, X., Saiyin, H., Lang, Q., Wan, B., Zhao, S., Yu, L. Septin1, a new interaction partner for human serine/threonine kinase aurora-B. Biochem. Biophys. Res. Commun. 336: 994-1000, 2005.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

14377 MW

6

Lymphocyte antigen 6A-2/6E-1

Cell membrane; Lipid-anchor, GPI-anchor.

Lymphocyte antigen 6A-2/6E-1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.