Anti-LECT1 CNMD Antilichaam

Boster Bio Anti-LECT1 CNMD Antibody catalog # A32278. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.

Leukocyte cell-derived chemotaxin 1 ; Chondromodulin

CNMD

O75829

Human, Mouse

Recombinant fusion protein of human LECT1 (NP_008946.1) .

Detected in cartilage and cardiac valves (at protein level) . Detected in the laminae fibrosa, spongiosa and ventricularis layers of normal cardiac valves (at protein level) . Expression is decreased cardiac valves of patients with valvular heart disease (at protein level) . Weakly expressed in chondrosarcoma.

WB, ICC, IF

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Liquid

Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A32278

37102 MW

Leukocyte cell-derived chemotaxin 1

Chondromodulin-1: Secreted, extracellular space, extracellular matrix. Accumulated in the inter- territorial matrix of cartilage.

Leukocyte cell-derived chemotaxin 1

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2