Anti-LEPREL1 P3H2 Antilichaam

Boster Bio Anti-LEPREL1 P3H2 Antibody catalog # A09235. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Prolyl 3-hydroxylase 2

P3H2

Q8IVL5

Human, Mouse, Rat

Recombinant fusion protein of human LEPREL1 (NP_060662.2) .

Expression localized to the epithelia of bile ducts and to the sacroplasm of heart muscle and skeletal muscle. In the pancreas, localized to a subpopulation of Langerhans islet cells and in the salivary gland, expressed in acinar cells (at protein level) (PubMed:15063763) . Expressed in adult heart, placenta, lung, liver, skeletal muscle and kidney (PubMed:15063763, PubMed:18487197) . Detected in fetal heart, spleen, lung, liver skeletal muscle and kidney (PubMed:18487197) .

WB

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

Prolyl 3-hydroxylase that catalyzes the post- translational formation of 3-hydroxyproline on collagens (PubMed:18487197) . Contributes to proline 3-hydroxylation of collagen COL4A1 and COL1A1 in tendons, the eye sclera and in the eye lens capsule (By similarity) . Has high activity with the type IV collagen COL4A1, and lower activity with COL1A1 (PubMed:18487197) . Catalyzes hydroxylation of the first Pro in Gly-Pro-Hyp sequences where Hyp is 4-hydroxyproline (PubMed:18487197) . Has no activity on substrates that lack 4- hydroxyproline in the third position (PubMed:18487197) .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A09235

80984 MW

WB: 1:500-1:2000

Prolyl 3-hydroxylase 2

Endoplasmic reticulum

Prolyl 3-hydroxylase 2

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2