Anti-Livin/Birc7 Antibody Picoband® fluoro647 Vervoeging

Baculoviral IAP repeat-containing protein 7 is a protein that in humans is encoded by the BIRC7 gene. This protein is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) and a RING finger motif. Its gene is mapped to 20q13.3. It has got 280- and 298- amino acids. The protein is highly expressed in melanomas while lowly expressed in some lymphomas, fetal kidney, fetal liver, testis and thymus. BIRC7 plays a vital role in blocking apoptosis induced.

Tumor necrosis factor ligand superfamily member 4; OX40 ligand; OX40L; CD252; Tnfsf4; Ox40l; Txgp1l

Birc7

329581

A2AWP0

Mouse

No cross-reactivity with other proteins.

E.coli-derived mouse Livin/Birc7 recombinant protein (Position: Q41-S285) .

Macrophages; peripheral blood leukocytes, lung, spleen and liver.

Flow Cytometry

Adaptive Immunity, Autoimmune, B Cells, Cell Type Markers, Cytokines, Immune System Diseases, Immunology, Innate Immunity, T Cells, TNF Superfamily

Immunogen affinity purified.

Liquid

Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.

1. Kasof GM, Gomes BC (May 2001) . Livin, a novel inhibitor of apoptosis protein family member. J Biol Chem 276 (5) : 3238–46. 2. Lin JH, Deng G, Huang Q, Morser J (Feb 2001) . KIAP, a novel member of the inhibitor of apoptosis protein family. Biochem Biophys Res Commun 279 (3) : 820–31. Entrez Gene: BIRC7 baculoviral IAP repeat-containing 7 (livin)

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Tumor necrosis factor (ligand) superfamily, member 4

Membrane; Single-pass type II membrane protein.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.