Anti-LLGL2 Antibody Picoband®

The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC) . In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Boster Bio Anti-LLGL2 Antibody Picoband® catalog # A08503-1. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

LLGL2

3993

Q6P1M3

Human

E.coli-derived human LLGL2 recombinant protein (Position: L102-Q553) . Human LLGL2 shares 91.2% amino acid (aa) sequence identity with mouse LLGL2.

WB, Flow Cytometry, ELISA

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

1. Gross, M. B. Personal Communication. Baltimore, Md. 6/24/2019. 2. Saito, Y., Li, L., Coyaud, E., Luna, A., Sander, C., Raught, B., Asara, J. M., Brown, M., Muthuswamy, S. K. LLGL2 rescues nutrient stress by promoting leucine uptake in ER+ breast cancer. Nature 569: 275-279, 2019. 3. Sripathy, S., Lee, M., Vasioukhin, V. Mammalian Llgl2 is necessary for proper branching morphogenesis during placental development. Molec. Cell. Biol. 31: 2920-2933, 2011.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A08503-1

120 kDa

6

IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.