Anti-LMBRD1 Antibody Picoband® APC-vervoeging

This gene encodes a lysosomal membrane protein that may be involved in the transport and metabolism of cobalamin. This protein also interacts with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F.

LMBRD1; C6orf209; NESI; BM-021; CD001; MSTP044; Probable lysosomal cobalamin transporter; HDAg-L-interacting protein NESI; LMBR1 domain-containing protein 1; Nuclear export signal-interacting protein

LMBRD1

55788

Q9NUN5

Human

No cross-reactivity with other proteins

E.coli-derived human LMBRD1 recombinant protein (Position: D67-A540) . Human LMBRD1 shares 93.9% amino acid (aa) sequence identity with both mouse and rat LMBRD1.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Buers, I., Pennekamp, P., Nitschke, Y., Lowe, C., Skryabin, B. V., Rutsch, F. Lmbrd1 expression is essential for the initiation of gastrulation. J. Cell. Molec. Med. 20: 1523-1533, 2016. 2. Dickinson, M. E., Flenniken, A. M., Ji, X., Teboul, L., Wong, M. D., White, J. K., Meehan, T. F., Weninger, W. J., Westerberg, H., Adissu, H., Baker, C. N., Bower, L., and 73 others. High-throughput discovery of novel developmental phenotypes. Nature 537: 508-514, 2016. Note: Erratum: Nature 551: 398 only, 2017. 3. Kawaguchi, K., Okamoto, T., Morita, M., Imanaka, T. Translocation of the ABC transporter ABCD4 from the endoplasmic reticulum to lysosomes requires the escort protein LMBD1. Sci. Rep. 6: 30183, 2016. Note: Electronic Article.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

61 kDa

6

LMBR1 domain containing 1

Lysosomal cobalamin transport escort protein LMBD1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.