Anti-LRDD/PIDD1 Antilichaam

P53-induced protein with a death domain (PIDD/LRDD) is a component of the PIDDosome. PIDD contains 910 residues with 7 leucine rich repeats (LRRs), 2 ZU-5 domains and a C-terminal death domain (DD) . PIDD can be cleaved into shorter fragments generating a PIDD-N fragment of 48 kD (residues 1-446), a PIDD-C fragment of 51 kD (residues 447-910) and a PIDD-CC fragment of 37 kD (residues 589-910) . Auto-cleavage of PIDD determines the downstream signaling events. The PIDD-C fragment mediates activation of NFκB via the recruitment of RIP1 and NEMO, while PIDD-CC causes caspase-2 activation, which leads to apoptosis.

Boster Bio Anti-LRDD/PIDD1 Antibody catalog # A10708-1. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human, Mouse, Rat.

PIDD-C; PIDD1; PIDD; p53-induced death domain-containing protein 1; Leucine-rich repeat and death domain-containing protein

PIDD1

Q9HB75

Human, Mouse, Rat

E.coli-derived human LRDD/PIDD1 recombinant protein (Position: A3-G348) .

WB, IHC, ICC, IF, IP, ELISA

Immunogen affinity purified.

500 μg/mL

Liquid

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A10708-1

P53-induced death domain protein 1

P53-induced death domain-containing protein 1

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.