Anti-LRRC1 Antibody Picoband®

Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble. The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells. Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions. It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues.

Boster Bio Anti-LRRC1 Antibody Picoband® catalog # A13956-2. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

LRRC1

55227

Q9BTT6

Human, Mouse, Rat

E.coli-derived human LRRC1 recombinant protein (Position: L120-R497) . Human LRRC1 shares 91.8% amino acid (aa) sequence identity with mouse LRRC1.

WB, ELISA

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

1. Saito, H., Santoni, M.-J., Arsanto, J.-P., Jaulin-Bastard, F., Le Bivic, A., Marchetto, S., Audebert, S., Isnardon, D., Adelaide, J., Birnbaum, D., Borg, J.-P. Lano, a novel LAP protein ly connected to MAGUK proteins in epithelial cells. J. Biol. Chem. 276: 32051-32055, 2001.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A13956-2

59 kDa

IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.