Anti-LRRC34 Antibody Picoband® fluoro550 Vervoeging
Gecertificeerd

Anti-LRRC34 Antibody Picoband® fluoro550 Vervoeging

Catalog #: A16000-1-Fluoro550
Maat: 100 µg/Vial

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Background

LRRC34 is a 419 amino acid protein that contains 2 LRR repeats. The gene encoding LRRC34 maps to chromosome 3, which encodes over 1,100 genes. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Synonyms

70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70 (S6K) alpha antibody, p70 (S6K) -alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Gene Name

LRRC34

Gene ID

151827

UniProt

Q8IZ02

Host

• Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross reactivity with other proteins.

Immunogen

E.coli-derived human LRRC34 recombinant protein (Position: M221-P464) . Human LRRC34 shares 82.6% and 80.2% amino acid (aa) sequence identity with mouse and rat LRRC34, respectively.

Clonality

• Polyclonal

Tissue Specificity

Expressed in all tissues.

Applications

Flow Cytometry

Field of Research

Signal Transduction, Signaling Pathway, Small G Proteins

Purification

Immunogen affinity purified.

Form

Liquid

Function

Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.

References & Citations

1. Gross, M. B. Personal Communication. Baltimore, Md. 9/25/2020. 2. Luhrig, S., Siamishi, I., Tesmer-Wolf, M., Zechner, U., Engel, W., Nolte, J. Lrrc34, a novel nucleolar protein, interacts with Npm1 and Ncl and has an impact on pluripotent stem cells. Stem Cells Dev. 23: 2862-2874, 2014. 3. Nolte, J. Lrrc34 interacts with Oct4 and has an impact on telomere length in mouse embryonic stem cells. Stem Cells Dev. 30: 1093-1102, 2021.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

52588 MW

Applications Notes

6

Gene Name Synonym

Serine/threonine-protein kinase AtPK1/AtPK6

Subcellular Location

Cytoplasm. Nucleus.

Protein Name

Serine/threonine-protein kinase AtPK1/AtPK6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Beschrijving

Anti-LRRC34 Antibody Picoband® fluoro550 Vervoeging Beschikbaar in 100 µg/Vial. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamAnti-LRRC34 Antibody Picoband® fluoro550 Vervoeging
Categorie
Beschikbare grootte100 µg/Vial
CatalogusnummerA16000-1-Fluoro550